Prof. Dr. Armin Zlomuzica

Prof. Dr. Armin Zlomuzica

Ruhr-Universität Bochum
Forschungs- und Behandlungszentrum für psychische Gesundheit (FBZ)
Klinische Psychologie und Psychotherapie

Massenbergstraße 9-13
44787 Bochum

Tel: +49 234 322 23 47
Email: armin.zlomuzica@rub.de

Vita

Arbeits- und Forschungsschwerpunkte

  • neuartige und innovative Behandlungsmöglichkeiten für emotionale Störungen

Gegenwärtige und frühere akademische Positionen

  • seit 2014: Juniorprofessor „Behavioral and Clinical Neuroscience”, Ruhr-Universität Bochum
  • 2009-2017: Weiterbildung zum Psychologischen Psychotherapeuten, Schwerpunkt Verhaltenstherapie
  • 2011-2014: Wissenschaftlicher Mitarbeiter, AE Klinische Psychologie und Psychotherapie (Prof. Dr. J. Margraf), Ruhr-Universität Bochum
  • 2009-2011: Wissenschaftlicher Mitarbeiter, AE Verhaltenspsychopharmakologie (Prof. Dr. E. Dere), Heinrich-Heine-Universität Düsseldorf
  • 2006–2009: Wissenschaftlicher Mitarbeiter, Institut für Experimentelle Psychologie, AE Physiologische Psychologie (Prof. Dr. J. P. Huston), Heinrich-Heine-Universität Düsseldorf
  • 2006–2008: Promotion (Dr. rer. nat.), Institut für Experimentelle Psychologie, AE Physiologische Psychologie (Prof. Dr. J. P. Huston), Heinrich-Heine-Universität Düsseldorf Thema der Dissertation: „Pharmacological and Genetic Modulation of Episodic-like Memory in the Mouse.” (Gesamtnote: magna cum laude)
  • 2000–2006: Wissenschaftliche Hilfskraft, Abteilung für Schlafmedizin und Neuropsychologie, Rhein-Ruhr Klinik, Essen
  • 1999–2005: Studium der Psychologie (Diplom), Heinrich-Heine-Universität Düsseldorf Thema der Diplomarbeit: „Der Einfluss von Schlaf auf falsche Erinnerungen im Deese-Roediger McDermott Paradigma.“ (Gesamtnote: sehr gut)

Akademische und psychotherapeutische Qualifikationen | Weiterbildungen

  • 2017:     Approbation Psychologischer Psychotherapeut, Schwerpunkt Verhaltenstherapie
  • 2010:     Projektleiter gem. §15 GenTSV einer gentechnischen Anlage zur Durchführung von gentechnischen Arbeiten der Sicherheitsstufe 1 gem. §3 Satz 1 Nr. 4 GenTG

Berufungsverfahren

  • 2014: Primo loco W1-Professur für „Behavioral and Clinical Neuroscience” an der Ruhr-Universität Bochum (Ruf angenommen)
  • 2012: Primo loco W1-Tenure Track Professur für Biologische Psychologie an der Universität Koblenz-Landau (Ruf abgelehnt)

Fördermittel | Auszeichnungen | Stipendien

  • 2016-2020: Mitglied des Jungen Kollegs der Nordrhein-Westfälischen Akademie der Wissenschaften und der Künste
  • 2016: Reisestipendium, Neuroscience and Psychotherapy Meeting, 20–21 March 2016, Nice, France
  • 2015: Mitglied der Global Young Faculty, Mercator Stiftung
  • 2013: Reisestipendium, International Behavioral Neuroscience Society, Dublin, Irland
  • 2011: Reisestipendium, DGPA Springschool “Genes, Brain, and Behavior”, St. Goar, Deutschland

Forschungsprojekte

  • 2020-2025: Zlomuzica A (Hauptantragssteller): Deutsche Forschungsgemeinschaft (DFG ZL 59/4-1). Heisenberg Programm. Titel: “Neue therapeutische Ansätze für Angststörungen“
  • 2020-2023: Zlomuzica A (Hauptantragssteller): Deutsche Forschungsgemeinschaft (DFG ZL 59/5-1). Sachbeihilfe. Titel: “Generalisierung in der Expositionstherapie“
  • 2017-2021: Zlomuzica A (Hauptantragssteller), Margraf J: Deutsche Forschungsgemeinschaft (DFG ZL 59/3-1). Teilprojekt im Rahmen des Sonderforschungsbereichs SFB 1280. Titel: “Extinction in the therapy context“
  • 2014-2017: Zlomuzica A (Hauptantragssteller), Schneider S, Margraf J: Deutsche Forschungsgemeinschaft (DFG ZL 59/2-2). Teilprojekt im Rahmen der Forschergruppe FOR 1581. Titel: “Exposure therapy outcome in specific phobia: the significance of extinction learning and stress system activity“
  • 2012-2014: Zlomuzica A (Hauptantragssteller), Schneider S, Margraf J: Deutsche Forschungsgemeinschaft (DFG ZL 59/2-1). Teilprojekt im Rahmen der Forschergruppe FOR 1581. Titel: “Clinical Implications of Extinction Learning and Renewal in Specific Phobia“
  • 2011: Zlomuzica A (Hauptantragssteller): Rektoratsfinanzierung der Ruhr-Universität Bochum, Titel: “The impact of genetic variation on extinction learning and symptom improvement during exposure-based psychotherapy”
Publikationen

Artikel in Peer-Reviewed Journalen

2020

  • Zlomuzica A, Raeder F, Schneider S, Konrad C, Merz CJ, Wolf OT, Margraf J (2020) Clinical implications of extinction learning in anxiety disorders. Neuroforum, in press.
  • Dere D, Zlomuzica A*, Dere E (2020) Fellow travellers in cognitive evolution: Co-evolution of working memory and mental time travel? Neuroscience and Biobehavioral Reviews, in press.
  • Raeder F, Merz CJ, Margraf J, Zlomuzica A (2020) The association between fear extinction, the ability to accomplish exposure and exposure therapy outcome in specific phobia. Scientific Reports, in press.

2019

  • Raeder F, Heidemann F, Margraf J, Zlomuzica A (2019) No pills, more chills: the adverse effect of hormonal contraceptive use on exposure therapy benefit. Journal of Psychiatry Research, in press.
  • Raeder F, Schneider S, Totzeck C, Adolph D, Margraf J, Zlomuzica A (2019) Reactivation of positive mastery experiences promotes exposure therapy benefit in height phobia. Cognitive Therapy and Research. In press.
  • Woud ML, Heeren A, Shkreli L, Meyer T, Egeri L, Cwik JC, Zlomuzica A, Kessler H, Margraf J (2019) Investigating the effect of proactive interference control training on intrusive memories. European Journal of Psychotraumatology,
  • Raeder F, Karbach L, Struwe H, Margraf J, Zlomuzica A (2019) Low perceived self-efficacy impedes discriminative fear learning. Frontiers in Psychology,
  • Raeder F, Merz CJ, Wolf OT, Margraf J, Zlomuzica A (2019) Post-exposure cortisol administration does not augment the success of exposure therapy: A randomized placebo- controlled study. Psychoneuroendocrinology, 99, 174-182.

2018

  • Zlomuzica A, Preusser F, Roberts S, Lester K, Dere E, Eley TC, Margraf J (2018) The role of KIBRA in reconstructive episodic memory. Molecular Medicine, 24: 7.
  • Zlomuzica A, Woud ML, Machulska A, Dietrich L, Kleimt K, Assion HJ, Wolf OT, Dere E, Margraf J (2018) Deficits in episodic memory and mental time travel in patients with post-traumatic stress disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 83:42-54.
  • Woud ML, Zlomuzica A, Cwik J, Margraf J, Shkreli L, Blackwell SE, Gladwin TE, Ehring T (2018) Effects of appraisal training on responses to recalling a distressing autobiographical event. Journal of Anxiety Disorders, 56:26-34.

2017

  • Preusser F, Margraf J, Zlomuzica A (2017) Generalization of extinguished fear to untreated fear stimuli after exposure. Neuropsychopharmacology, 13:2545-2552.
  • Zlomuzica A, Machulska A, Roberts S, von Glischinski M, Rinck M, Lester KJ, Eley TC, Margraf J (2017) The dopamine D2 receptor mediates approach-avoidance tendencies in smokers. European Archives of Psychiatry and Clinical Neuroscience, 268:261-268.
  • Dere E, Dere D, de Souza Silva MA, Huston JP, Zlomuzica A (2017) Fellow travellers: Working memory and mental time travel in rodents. Behavioural Brain Research, 17:30255-3.

2016

  • Dere E, Zlomuzica A, Staniloiu A, Markowitsch HJ (2016) Editorial: Progress in Episodic Memory Research. Frontiers in Behavioral Neuroscience, 10:61
  • Machulska A, Zlomuzica A, Rinck M, Assion HJ, Margraf J (2016) Approach bias modification in inpatient psychiatric smokers. Journal of Psychiatric Research, 76:44-51.
  • Breeden P, Dere D, Zlomuzica A*, Dere E* (2016) The mental time travel continuum: On the architecture, capacity, versatility and extension of the mental bridge into the past and future. Reviews in the Neurosciences, 27:421-34.
  • Woud ML, Zhang XC, Becker ES, Zlomuzica A, Margraf J (2016) Catastrophizing Misinterpretations Predict Somatoform-Related Symptoms and New Onsets of Somatoform Disorders. Journal of Psychosomatic Research, 81:31-7
  • Zlomuzica A, Dere D, Binder S, DeSouza Silva MA, Huston JP, Dere E (2016) Neuronal histamine and cognitive symptoms in Alzheimer’s disease. Neuropharmacology, 15:188-4
  • Zlomuzica A, Preusser F, Totzeck C, Dere E, Margraf J (2016) The Impact of Different Emotional States on the Memory for What, Where and When Features of Specific Events. Behavioural Brain Research, 298:181-87

2015

  • Binder S, Dere E, Zlomuzica A (2015) A critical appraisal of the what-where-when episodic- like memory test in rodents: Achievements, caveats and future directions. Progress in Neurobiology, 130:71-85
  • Zlomuzica A, Preusser F, Schneider S, Margraf J (2015) Increased perceived self-efficacy facilitates the extinction of fear in healthy participants. Frontiers in Behavioral Neuroscience, 9:270
  • Margraf J, Zlomuzica A (2015) Changing the future rather than the past: Towards a translational paradigm shift in treating anxiety disorders. EMBO Reports, 16:259-60

2014

  • Machulska A*, Zlomuzica A*, Adolph D, Rinck M, Margraf J (2014) “A cigarette a day keeps the goodies away”: Smokers show automatic approach tendencies for smoking - but not for food-related stimuli. PLOS One, 10:2: e0116464
  • Mosig C, Merz CJ, Mohr C, Adolph D, Wolf OT, Schneider S, Margraf J, Zlomuzica A (2014) Enhanced discriminative fear learning of phobia-irrelevant stimuli in spider-fearful individuals. Frontiers in Behavioral Neuroscience, 8:328
  • Ambree O, Buschert J, Zhang W, Arolt V, Dere E, Zlomuzica A (2014) Impaired spatial learning and reduced adult hippocampal neurogenesis in histamine H1-receptor knockout mice. European Neuropsychopharmacology, 24:1394-404
  • Dere E & Zlomuzica A (2014) Far beyond declarative and non-declarative memories. Frontiers in Behavioral Neuroscience, 8:173
  • Zlomuzica A, Dere D, Machulska A, Adolph D, Dere E, Margraf J (2014) Episodic memories in anxiety disorders: Clinical implications. Frontiers in Behavioral Neuroscience, 8:131

2013

  • Ebel P, vom Dorp K, Petrasch-Parwez E, Zlomuzica A, Kinugawa K, Mariani J, Minich D, Ginkel C, Degen J, Eckhardt M, Dere E, Dörmann P, Willecke K (2013) Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities. Journal of Biological Chemistry, 288:21433-47
  • Zlomuzica A, Dere D, Dere E (2013) The histamine H1 receptor and recollection-based discrimination in a temporal order memory task in the mouse. Pharmacology Biochemistry and Behavior, 111: 58-63
  • Pause BM, Zlomuzica A, Kinugawa K, Mariani J, Pietrowsky R, Dere E (2013) Perspectives on episodic-like and episodic memory. Frontiers in Behavioral Neuroscience, 7:33
  • Kinugawa K, Schumm S, Pollina M, Depre M, Jungbluth C, Doulazmi M, Sebban C, Zlomuzica A, Pietrowsky R, Pause B, Mariani J, Dere E (2013) Aging-related episodic memory decline: are emotions the key? Frontiers in Behavioral Neuroscience, 7:2
  • Zlomuzica A, Burghoff S, Schrader J, Dere E (2013) Superior working memory and behavioural habituation but diminished psychomotor coordination in mice lacking the ecto- 5'-nucleotidase (CD73) gene. Purinergic Signalling, 9:175-82
  • Ginkel C, Hartmann D, Vom Dorp K, Zlomuzica A, Farwanah H, Eckhardt M, Sandhoff R, Degen J, Rabionet M, Dere E, Doermann P, Sandhoff K, Willecke K (2012) Ablation of neuronal Ceramide Synthase 1 in mice decreases ganglioside levels and expression of Myelin Associated Glycoprotein in oligodendrocytes. Journal of Biological Chemistry, 287:41888-902

2012

  • Zlomuzica A, Tress O, Binder S, Willecke K, Dere E (2012) Changes in object recognition and anxiety-like behaviour in mice expressing a Cx47 mutation that causes Pelizaeus- Merzbacher-like Disease. Developmental Neuroscience, 34:277-87
  • Tress O, Maglione M, May D, Pivneva T, Seyfarth J, Binder S, Zlomuzica A, Theis M, Dere E, Kettenmann H, Willecke K (2012) Panglial gap junctional communication is essential for maintenance of myelin in the central nervous system. Journal of Neuroscience, 32:7499-518
  • Dere E, Zlomuzica A (2012) The role of gap junctions in the brain in health and disease. Neuroscience & Biobehavioral Reviews, 36:206-17
  • Zlomuzica A, Viggiano D, Degen J, Binder S, Ruocco LA, Sadile AG, Willecke K, Huston JP, Dere E (2012) Behavioral alterations and changes in Ca/Calmodulin kinase II levels in the striatum of connexin 36 deficient mice. Behavioural Brain Research, 226:293-300

2011

  • Tress O, Maglione M, Zlomuzica A, May D, Dicke N, Degen J, Dere E, Kettenmann H, Hartmann D, Willecke K (2011) Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation associated with Pelizaeus-Merzbacher-like disease in humans. PLOS Genetics, 7:7: e1002146

2010

  • Dere E, Zlomuzica A, De Souza Silva MA, Ruocco LA, Sadile AG, Huston JP (2010) Neuronal histamine and the interplay of memory, reinforcement and emotions. Behavioural Brain Research, 215:209-20
  • Zlomuzica A, Reichinnek S, Maxeiner S, Both M, May E, Wörsdörfer P, Draguhn A, Willecke K, Dere E (2010) Deletion of connexin45 in mouse neurons disrupts one-trial object recognition and alters kainate-induced gamma-oscillations in the hippocampus. Physiology and Behavior, 101:245-53

2009

  • Zlomuzica A, Ruocco LA, Sadile AG, Huston JP, Dere E (2009) Histamine H1-receptor knockout mice exhibit impaired spatial memory in the eight-arm radial maze. British Journal of Pharmacology, 157:86-91

2008

  • Dere E, Zlomuzica A, Viggiano D, Ruocco LA, Watanabe T, Sadile AG, Huston JP, De Souza Silva MA (2008) Episodic-like and procedural memory impairments in histamine H1-receptor knockout mice coincide with changes in acetylcholine esterase activity in the hippocampus and dopamine turnover in the cerebellum. Neuroscience, 157:532-541
  • Zlomuzica A, Viggiano D, De Souza-Silva MA, Ishizuka T, Gironi Carnevale UA, Ruocco LA, Watanabe T, Sadile AG, Huston JP, Dere E (2008) The histamine H1-receptor mediates the motivational effects of novelty. European Journal of Neuroscience, 27:1461-1474
  • Dere E, Zheng-Fischhöfer Q, Viaggiano D, Gironi Carnevale UA, Rocco LA, Zlomuzica A, Schnichels M, Willecke K, Huston JP, Sadile A (2008) Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, AChE levels in the striatum, and CREB levels in the striatum and piriform cortex. Neuroscience, 153:396-405
  • Zlomuzica A, Dere E, Huston JP, De Souza Silva MA (2008) The selective NK3 receptor agonist senktide promotes episodic-like memory in mice. Neurobiology of Learning and Memory, 90:420-425

2007

  • Zlomuzica A, De Souza Silva MA, Huston JP, Dere E (2007) NMDA-receptor modulation by D- cycloserine promotes episodic-like memory in mice. Psychopharmacology, 193:503-509

* geteilte Erst- und Letztautorenschaft

Buchkapitel (Peer-Reviewed)

  • Zlomuzica A, Schneider S, Margraf J (2020) Panikstörung und Agoraphobie. In: Leibing, Eric (Ed.): Lehrbuch der Psychotherapie für die Ausbildung zur/zum Psychologischen PsychotherapeutIn und für die ärztliche Weiterbildung. München: CIP-Medien, im Druck.
  • Von Brachel R, Zlomuzica A, Teisman T (2019) Verhaltensaktivierung. In: Margraf J, Schneider S (Ed.): Lehrbuch der Verhaltenstherapie. Springer-Verlag Berlin Heidelberg, im Druck.
  • Zlomuzica A (2019) Das rekonstruktive Gedächntis. In: Michels, Cchristoph (Ed.): Das Gedächtniskonzept aus dem Blickwinkel der interdisziplinären Forschung. Paderborn: Verlag Ferdinand Schöningh, im Druck.
  • Zlomuzica A, Binder S, Dere E (2013) Chapter 1: Gap junctions in the brain. In: Dere E. (Ed.) Gap Junctions in the Brain: Physiological and Pathological Roles. San Diego, CA: Academic Press, pp. 3-17.
  • Zlomuzica A, Avci XH, Dere E (2013) Chapter 26: The behavioral genetics of gap junctions. In: Dere E (Ed.) Gap Junctions in the Brain: Physiological and Pathological Roles. San Diego, CA: Academic Press, pp. 277-283.
  • Dere E, Zlomuzica A, De Souza Silva A, Huston JP (2013) Object recognition in the mouse. In: Crusio WE, Sluyter F, Gerlai RT, Pietropaolo S (Eds.) Behavioral Genetics of the Mouse: Volume I. Genetics of Behavioral Phenotypes. Cambridge: University Press, pp. 331-337.
  • Dere E, Ambree O, Zlomuzica A (2012) Histidine Decarboxylase. In: Mello JPF (Ed.) Amino Acids in Human Nutrition and Health. Section 1: Enzymes. Oxfordshire: Cabi Publishing, pp. 89-102.
  • Dere E, Zlomuzica A, Huston JP, De Souza Silva, MA (2008) Chapter 2.2: Animal episodic memory. In: Dere E, Easton A, Nadel L, Huston JP (Eds.) Handbook of Episodic Memory. Vol. 18. Amsterdam: Elsevier Science, pp. 155-184.

Zurück →